Cardiovascular
Clinical reference
Aortic Stenosis
Aortic stenosis is narrowing of the aortic valve. Severe AS defined as valve area <1.0 cm². Classic triad: angina, syncope, dyspnea. TAVR has transformed treatment.
AS
aortic valve stenosis
calcific aortic stenosis
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Core official overview
What this condition is
What are heart valve diseases?Heart valve disease happens when one or more of your heart valves don't work well.Your heart has four valves: the tricuspid, pulmonary, mitral, and aortic valves. The valves have flaps that open and close. The flaps make sure that blood flows in the right direction through your heart and to the rest of your body. When your heart beats, the flaps open to let blood through. Between heartb…
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Recruiting clinical trials
Additional official research
RECRUITING
NA
NCT06689839
The objective of this study is to compare the safety and effectiveness of the F2 Cerebral Protection System (CPS) to a standard of care control group in patients undergoing Transcatheter Aortic Valve Replacement (TF TAVR)
RECRUITING
PHASE4
NCT05721170
This is a prospective, multicentre, investigator-initiated, randomized clinical trial clinical trial investigating the impact of beta-blockers administration among patients undergoing TAVI for severe aortic valve stenosis. Adults already r…
RECRUITING
NA
NCT07107568
The goal of this clinical trial is to determine whether a non-invasive coronary assessment strategy using photon-counting detector computed tomography (PCD-CT) is non-inferior to invasive coronary angiography (ICA) for evaluating coronary…
RECRUITING
N/A
NCT04454177
The purpose of this study is to observe conduction disturbance, daily activity level, heart rates, oxygen saturation in patients who underwent Transcatheter Aortic Valve Replacement (TAVR) and to evaluate the utility of the HUAWEI Watch (H…
RECRUITING
NA
NCT05511792
To compare down sizing strategy versus annular sizing strategy technique (control group) in Type 0 bicuspid aortic stenosis (AS) patients undergoing transcatheter aortic valve replacement (TAVR) with self-expanding valves (SEVs): a randomi…
RECRUITING
NA
NCT06472934
This is a multi-centric, open-label, randomized trial to evaluate the safety and efficacy of temporary discontinuation of beta-blocker treatment in patients undergoing transcatheter aortic valve replacement.
RECRUITING
N/A
NCT06722066
The goal of this observational study is to learn about the long-term effects of aortic valve annular calcification in patients undergoing transcatheter aortic valve replacement (TAVR). The main question it aims to answer is: Does the degre…
RECRUITING
NA
NCT06859255
The general objective of this study is to compare in vitro and in vivo the hemodynamic performance of different types of aortic valve prostheses and possible surgical implantation techniques. The study involves the collection of data deriv…
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