Cardiovascular
Clinical reference
Mitral Regurgitation
Mitral regurgitation is backflow through an incompetent mitral valve. Acute MR (papillary muscle rupture post-MI) is a surgical emergency. Chronic MR is often well tolerated.
MR
mitral insufficiency
mitral incompetence
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Core official overview
What this condition is
What is the mitral valve?The mitral valve is one of the four valves in your heart. Heart valves have flaps that open and close. The flaps make sure that blood flows in the right direction through your heart and to the rest of your body. When your heart beats, the flaps open to let blood through. Between heartbeats, they close to stop the blood from flowing backwards.The mitral valve opens to let blood flow from your…
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Recruiting clinical trials
Additional official research
RECRUITING
N/A
NCT06805253
Investigators assume that surgical correction approach to functional mitral regurgitation during intervention for chronic aortic regurgitation in patients with severe enlargement of the left heart chambers influences reverse remodeling of…
RECRUITING
NA
NCT04820764
Safety and performance evaluation of the CardioMech Mitral Valve Repair System (MVRS) in patients with degenerative mitral valve regurgitation.
RECRUITING
N/A
NCT06235385
This study aims to investigate the prevalence and characteristics of multiple and mixed valvular heart disease (MMVD), which includes combinations of stenotic or regurgitant lesions on cardiac valves. The research will be conducted as a mu…
RECRUITING
NA
NCT04029337
Study to evaluate the feasibility, safety and performance of the HighLife trans-septal Transcatheter Mitral Valve in patients with moderate-severe and severe mitral regurgitation who are at high risk for surgical treatment.
RECRUITING
NA
NCT06684171
Mitral regurgitation (MR) is a common valvular heart disease in the elderly population, frequently associated with poor prognosis if not treated. Transcatheter edge-to-edge repair (TEER) has recently emerged as a popular strategy due to mi…
RECRUITING
NA
NCT04913727
The investigators' hypothesis is that CMR tissue characterization and myocardial function analysis acquired by CMR feature tracking technique predict reverse remodeling in patients with severe secondary mitral regurgitation (MR) undergoing…
RECRUITING
N/A
NCT03962023
Degenerative mitral insufficiency secondary to valve prolapse is the most common valve disease in Western countries. In the absence of specific treatment, it spontaneously progresses to heart failure and death when it is severe. Surgical m…
RECRUITING
NA
NCT07741383
This study aims to evaluate the safety and efficacy of combined electrical cardioversion and TEER in patients with severe mitral regurgitation and atrial fibrillation after undergoing TEER. The main objective is to assess the superiority o…
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