Mitral Regurgitation

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Cardiovascular Clinical reference

Mitral Regurgitation

Mitral regurgitation is backflow through an incompetent mitral valve. Acute MR (papillary muscle rupture post-MI) is a surgical emergency. Chronic MR is often well tolerated.

MR mitral insufficiency mitral incompetence
Terms
0
ICD-10
1
Evidence
5
Trials
8
Core official overview

What this condition is

What is the mitral valve?The mitral valve is one of the four valves in your heart. Heart valves have flaps that open and close. The flaps make sure that blood flows in the right direction through your heart and to the rest of your body. When your heart beats, the flaps open to let blood through. Between heartbeats, they close to stop the blood from flowing backwards.The mitral valve opens to let blood flow from your…

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Recruiting clinical trials

Additional official research

RECRUITING NA

Multimodal Investigation of Neural Plasticity

NCT06453980

This study will evaluate the effects of a form of non-invasive brain stimulation on brain functioning and memory in cognitively intact older adults (healthy controls, HC) and in those with mild cognitive impairment (MCI).

RECRUITING NA

Capstan Medical TMVR Study: FIH

NCT06600191

This study is a prospective, multi-center, non-randomized first in human study to evaluate the safety and feasibility of the Capstan Medical TMVR System for intervention in adults with moderate-severe or greater mitral regurgitation who ar…

RECRUITING NA

A New Diagnostic Algorithm to Non-invasively Track Fibrotic Changes in Myeloproliferative Neoplasms Based on C-C Chemokine Receptor 2 Detection. From Flow Cytometry to the Development of Targeted Positron Emission Tomography Molecular Imaging. Pre-clinical Studies and First In-human Proof of Concept

NCT07419178

Chronic "Philadelphia-negative" myeloproliferative syndromes are chronic blood disorders. They include essential thrombocythemia, polycythemia vera, and myelofibrosis. Myelofibrosis may arise de novo ("primary myelofibrosis") or represent…

RECRUITING NA

ATLAS (AltaValve) Pivotal Trial

NCT06465745

This is a prospective, single arm, multicenter, clinical trial designed to evaluate the safety and performance of the AltaValve System for the treatment of mitral regurgitation in a targeted patient population.

RECRUITING NA

Early Transcatheter Mitral Valve Repair After Myocardial Infarction

NCT06282042

To explore the impact of early transcatheter edge-to-edge repair of acute functional mitral regurgitation after myocardial infarction on the combined incidence of death and heart-failure associated hospitalisations at one-year follow-up, a…

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